Our Research Group

Yesil-Celiktas research group applies a multidisciplinary approach to design and develop organ-on-chip platforms that enable us to elucidate cellular and molecular mechanisms governing tissue pathology or offering protection during injury. Our research lies at the intersection of neuronal and pulmonary diseases, immuno-microbiology, tissue engineering, and biomaterials. Ultimately, our goal is to discover novel drug targets and personalized diagnostics using microengineered systems that recapitulate complex human organ pathophysiology in vitro. As part of on-going research, Rett syndrome-on-a-chip model is being developed, neural responses to inflammation are being addressed by cerebral organoid-on-chip model, whereas cellular responses to environmental pollutants are examined in the small airway-on-chip platform. Our lab is translationally focused and pursues high-risk research. We thrive to positively impact human health and our society through our discoveries.