Our Research Group
Yesil-Celiktas research group applies a multidisciplinary approach to design and develop organ-on-chip platforms that enable us to elucidate cellular and molecular mechanisms governing tissue pathology or offering protection during injury. Our research lies at the intersection of neuronal and pulmonary diseases, immuno-microbiology, tissue engineering, and biomaterials. Ultimately, our goal is to discover novel drug targets and personalized diagnostics using microengineered systems that recapitulate complex human organ pathophysiology in vitro. As part of on-going research, Rett syndrome-on-a-chip model is being developed, neural responses to inflammation are being addressed by cerebral organoid-on-chip model, whereas cellular responses to environmental pollutants are examined in the small airway-on-chip platform. Our lab is translationally focused and pursues high-risk research. We thrive to positively impact human health and our society through our discoveries.
News
- Our latest publications
Yusuf Caglar Odabasi, Sena Yanasik, Pelin Saglam-Metiner, Yasin Kaymaz*, and Ozlem Yesil-Celiktas*
Pelin Saglam-Metiner, Elif Duran, Leila Sabour-Takanlou, Cigir Biray-Avci & Ozlem Yesil-Celiktas
Congratulations to Professor Ozlem Yesil-Celiktas for receiving the Ege University’s “Science and Engineering” award.
- Microchip Models of Human Lungs Enable Better Understanding of Disease, Immune Response
IMAGE: SIMPLIFIED SCHEMATIC MODEL OF THE HUMAN LUNG WITH HEALTHY AND VIRUS-INFECTED ALVEOLAR SACS ALONG WITH A VIRAL INFECTION ON A LUNG ALVEOLUS PLATFORM.
Lung-on-a-chip platforms can provide a more rapid alternative for preliminary testing of drug candidates to treat coronavirus-induced lung infections.
In Biomicrofluidics, by AIP Publishing, researchers from Ege University and the University of Nottingham review a range of lung-on-chip technologies that represent the vital properties of lung tissue and are capable of recapitulating the fundamental aspects of various pathologies.
Selected Publications
2023
2022
2021
2020
2019
2018
Contact
Prof. Dr. Ozlem Yesil-Celiktas
+90-232-3115813
Ege University
Department of Bioengineering
35040 Bornova-Izmir/TURKEY